three.5 (2 votes)

Healthcare Prof:

The economic situation does not appear to have affected the cosmetic surgery business in Britain: new figures from a not-for-profit organisation show that the number of surgical procedures were 6.7 per cent higher in 2009 than 2008, among which the number of male breast reductions went up by 80 per cent.

These figures, released on 1st February, are from the latest audit by the British Association of Aesthetic Plastic Surgeons (BAAPS), a not-for-profit organisation that describes its purpose as being to advance the education and practice of Aesthetic Plastic Surgery for public benefit.

Despite the recession, mentioned the BAAPS in a press statement, 36,482 surgical procedures took place in Britain last year, up from 34,187 in 2008.

The audit also highlighted that:In females, procedures went up from 31,183 in 2008 to 32,859 in 2009 (just over five per cent increase).In males, procedures went up from 3,004 in 2008 to 3,623 in 2009 (21 per cent enhance).In males, the quantity of breast reduction or or gynaecomastia operations (to remove “man boobs”) went up from 323 in 2008 to 581 in 2009 (80 per cent boost).Breast reduction went from the 5th to the 3rd most popular procedure for guys.Breast reduction is still popular among women: it rose from 3,522 operations in 2008 to 4,122 in 2009 (17 per cent increase).Male brow lifts went up from 72 in 2008 to 109 in 2009, male facelifts went up by 23 per cent and male tummy tucks by 20 per cent.”Nose jobs” (rhinoplasty) went up 25 per cent overall for both sexes, and is now the 5th most popular procedure (in 2008 it was the 5th).Though girls in 2009 demanded 8 per cent fewer facelifts than they did in 2008, they have steadily demanded more brow lifts, eyelid surgery and nose jobs, suggesting they have sought cheaper and much more targeted ways of looking younger.Breast enlargement is still probably the most popular procedure, with 8,565 performed in 2009, a rise of 1 per cent on 2008.Nigel Mercer, consultant plastic surgeon and President of BAAPS, told the media that people’s interest in aesthetic surgery appears to remain strong, and is even growing among British guys, despite the economic situation.

“Wide media coverage has clearly helped to educate both males and ladies about the latest advances and choices available along with the potential risks of these treatments,” said Mercer, who said he was encouraged that a lot more and more people are choosing surgeons with good training and qualifications, including those featured on the BAAPS website.

“In the current climate it truly is even a lot more essential that patients seeking cosmetic surgical procedures don’t make decisions based solely on price,” he warned.

The most popular procedure overall, with out distinguishing among guys and ladies, in 2009 was breast augmentation. The second was eyelid operations, third was breast reduction (up from 4th place in 2008), fourth was face/neck lift (dropped from 3rd place in 2008), fifth was rhinoplasty (nose job, up from 7th place in 2008), sixth was liposuction, seventh was tummy tuck (down from 5th place in 2008), eighth was brow lift (up from 9th place in 2008), and ninth was otoplasty (ear correction, dropped from 8th place in 2008).

For females, probably the most popular procedure in 2009 was breast augmentation, second was blepharoplasty (eyelids), third was breast reduction (up from 5th place in 2008), fourth was face/neck lift (dropped from 3rd place in 2008), and fifth was tummy tuck (dropped from 4th place in 2008).

Source: BAAPS.

Written by: Catharine Paddock, PhD
Copyright: Medical News Today
Not to be reproduced with out permission of Medical News Today

four (1 votes)

Healthcare Prof:

5 (3 votes)

A just published investigation experiment on inactive men with high blood pressure shows that just 3 months of soccer practise twice a week causes a significant fall in blood pressure, resting pulse rate, and percentage of body fat, and is much more effective than the doctor’s usual advice on healthy diet and exercise. Other parallel experiments on each females and males further demonstrates that a regular game of soccer affects numerous cardiovascular danger factors for example maximal oxygen uptake, heart function, elasticity of the vascular system, blood pressure, cholesterol and fat mass far far more than e.g. strength training and just as much if not much more than running.

Each of the experiments was controlled randomized studies exactly where the soccer groups had been compared to other exercise groups and inactive controls. The soccer experiments are part of a large-scale study project on soccer and health carried out in the University of Copenhagen, four Danish University Hospitals, the Swiss Federal Institute of Technology and the Schulthess Clinic in Zurich.

Project Leader and Associate Professor in the University of Copenhagen Peter Krustrup recaps the final results: “Our investigation shows that soccer is really a versatile and intense type of exercise that provides a positive impact on cardiovascular threat factors in a large group of untrained adult males and women,” and continues: “Based on the final results, soccer might be recommended as part with the therapy for high blood pressure and as broad-spectred prevention of cardiovascular diseases.”

Small games, big gains

When untrained children, teens, adults and older people play soccer, their pulse rate remains high and they perform many intense actions like sprints, turns, kicks and tackles.

“Our analyses also showed that the pulse rate and activity profile will be the identical in small-sided games where only 4, 6, 8 or 14 people play. In other words, it’s very easy to obtain a combination of cardio and strength training with soccer,” concludes Krustrup

Research partner Lars Juel Andersen from the Clinic of Sport Cardiology at Gentofte Hospital, Denmark, believes that the final results are very good news for the millions of people worldwide, suffering from high blood pressure: “It is properly known that physical inactivity is really a substantial risk factor in developing cardiovascular diseases in itself, but it really is new that a pleasurable team sport like soccer is effective in treating high blood pressure”. Furthermore, associate professor Peter Riis Hansen from Gentofte Hospital suggests that football could have other favourable effects on the vascular system, namely a reduction of arterial stiffness, which has been associated with improved cardiovascular outcomes.

About the project

Led by Professors Peter Krustrup and Jens Bangsbo from Department of Exercise and Sports Sciences, University of Copenhagen, 50 researchers from seven nations have studied the physical, psychological and social aspects of soccer and the outcomes are remarkable. Numerous scientific articles from the project are published on 2 February 2010 at a seminar at the University of Copenhagen and later this month the Scandinavian Journal of Medicine and Science in Sports will publish a special edition problem entitled “Football for Health” containing 14 scientific articles from the soccer project. The study project has received funding from FIFA – Medical Assessment and Investigation Centre (F-MARC), The Danish Ministry of Culture, TrygFonden, United Federation of Danish Workers (3F), The Danish Football Association, Team Denmark and The Danish Sports Confederation.

Further analysis plans:

The researchers have distinct plans to examine the impact of soccer on other patient groups for example people with diabetes II and cancer. The research group is also planning a follow-up study of the long-term effects of soccer on high blood pressure and preliminary stages of osteoporosis. A planned collaboration with an international network of researchers from, among other people, England, Italy, Portugal, Switzerland, Germany, Norway, Sweden, USA, Kenya and Iran will examine the cardiovascular and muscular-skeletal effects of soccer and other ball games for example basketball, handball, volleyball and floorball on inactive and overweight children and inactive elderly people.

Source:
Peter Krustrup
University of Copenhagen

4 (7 votes)

Healthcare Prof:

4.4 (five votes)

Male homosexuality doesn’t make complete sense from an evolutionary point of view. It appears that the trait is heritable, but because homosexual males are much less likely to produce offspring than heterosexual guys, shouldn’t the genes for this trait have been extinguished long ago? What value could this sexual orientation have, that it has persisted for eons even with no any discernible reproductive advantage?

One feasible explanation is what evolutionary psychologists call the “kin selection hypothesis.” What that means is the fact that homosexuality may possibly convey an indirect benefit by enhancing the survival prospects of close relatives. Specifically, the theory holds that homosexual males might enhance their own genetic prospects by being “helpers inside the nest.” By acting altruistically toward nieces and nephews, homosexual males would perpetuate the family genes, which includes some of their own.

Two evolutionary psychologists, Paul Vasey and Doug VanderLaan of the University of Lethbridge, Canada tested this idea for the past several years on the Pacific island of Samoa. They chose Samoa because males who prefer men as sexual partners are widely recognized and accepted there as a distinct gender category – called fa’afafine – neither man nor woman. The fa’afafine tend to be effeminate, and exclusively attracted to adult men as sexual partners. This clear demarcation makes it easier to identify a sample for study.

Past research has shown that the fa’afafine are much a lot more altruistically inclined toward their nieces and nephews than either Samoan girls or heterosexual men. They are willing to babysit a lot, tutor their nieces and nephews in art and music, and help out financially – paying for medical care and education and so forth. In a new study, the scientists set out to unravel the psychology with the fa’afafine, to see if their altruism is targeted specifically at kin as opposed to kids in general.

They recruited a large sample of fa’afafine, and comparable samples of women and heterosexual men. They gave them all a series of questionnaires, measuring their willingness to help their nieces and nephews in several ways – caretaking, gifts, teaching – and also their willingness to do these things for other, unrelated kids. The findings, reported on-line this week in the journal Psychological Science, lend strong assistance to the kin selection idea. Compared to Samoan ladies and heterosexual men, the fa’afafine showed a much weaker link between their avuncular – or uncle like – behavior and their altruism toward kids generally. This cognitive dissociation, the scientists argue, allows the fa’afafine to allocate their resources more efficiently and precisely to their kin – and thus enhance their own evolutionary prospects.

To compensate for being childless, each fa’afafine would have to somehow assistance the survival of two extra nieces or nephews who would otherwise not have existed. “If kin selection may be the sole mechanism by which genes for male same-sex sexual attraction are maintained more than time,” the fa’afafine must be “super uncles” to earn their evolutionary keep, explains Vasey. Consequently, Vasey suggests “that the fa’afafine’s avuncularity probably contributes to the evolutionary survival of genes for male same-sex sexual attraction, but is unlikely to entirely offset the costs of not reproducing.”

Do these findings have any meaning outside of Samoa? Yes and no. Samoan culture is really distinct from most Western cultures. Samoan culture is extremely localized, and centered on tight-knit extended families, whereas Western societies tend to be highly individualistic and homophobic. Families are also much far more geographically dispersed in Western cultures, diminishing the role that bachelor uncles can play within the extended loved ones, even if they choose to. But in this sense, the researchers say, Samoa’s communitarian culture might be a lot more – not less – representative of the environment in which male same-sex sexuality evolved eons ago. In that sense, it’s not the bachelor uncle who is poorly adapted towards the world, but rather the modern Western world that has evolved into an unwelcoming place.

Source:
Catherine Allen-West
Association for Psychological Science
Copyright: Medical News Today
Not to be reproduced with out permission of Medical News Right now

three (1 votes)

Healthcare Prof:

Most of us probably think of sperm as rather active small cells, swimming with quick movements of their “tail” or flagella. But actually sperm’s motility is in fact short lived. When within the male reproductive tract they have to rest easy, lest they wear themselves out prematurely and give up any chance of ever finding an egg.

Scientists have long known that sperm’s activity level depends on their internal pH. And now — after many years of looking – researchers reporting inside the February 5th problem with the journal Cell, a Cell Press publication, have finally located the channel that allows the tiny cells to rid themselves of protons. Once within the female reproductive tract, that proton release alterations their internal environment from acidic to alkaline and begins their race towards the finish line.

The findings offer new insight into a critical event in human fertilization and may lead to new ways of controlling male fertility, according to the researchers.

“The concentration of protons inside the [sperm] cell is 1,000 times higher than outside,” mentioned Yuriy Kirichok of the University of California, San Francisco. “If you just open a pore, protons will go outside. We identify the molecule that lets them out.”

Kirichok likens the quiescent sperm cells to balloons inflated with protons instead of air. If you open a hole in the sperm, protons will readily flow out. In fact, each sperm’s flagellum is covered in numerous so-called Hv1 proton channels, they show. When the channels are activated by external cues, the flood gates open and protons escape from numerous pores at once.

Kirichok said there are many conditions that open up the Hv1 pore, such as alkaline conditions and the removal of zinc outside the cell. They also open when exposed towards the endocannabinoid known as anandamide, a substance which is present in both the male and female reproductive tracts and that might be at particularly high levels in the vicinity with the egg.

That raises an interesting possibility, Kirichok stated. Endocannabinoids are natural lipids that influence the activity of neurons. They are so named because they act on the same receptors that the active component of marijuana does. It remains to be shown, but that connection might explain why marijuana has been linked to impaired male fertility.

“Marijuana likely activates sperm prematurely, leaving them burnt out in a matter of hours,” Kirichok said.

Perhaps most importantly, the newly discovered Hv1 channel may allow for new ways to modify the activity of sperm in either direction, Kirichok mentioned. In fact, several key biochemical reactions in sperm depend on intracellular pH levels, such as its initial activation, hyperactivation once near the fallopian tubes and the acrosome reaction, in which enzymes are released to penetrate the egg.

“All of these events are essential to fertilization,” Kirichok mentioned. “You can imagine now that we know the molecule responsible we could block it to avoid activation and fertilization as a type of male contraception.” On the other hand, you might also give some sperm the extra boost they want.

The researchers include Polina V. Lishko, Inna L. Botchkina, Andriy Fedorenko, and Yuriy Kirichok, at University of California, San Francisco, San Francisco, CA.

Source:
Cathleen Genova
Cell Press

four.91 (45 votes)

Healthcare Prof:

5 (14 votes)

How safe is circumcision? A systematic review, published inside the open access journal BMC Urology has discovered that neonatal and infant circumcision by trained staff rarely final results in issues. Risks can be higher amongst older boys, especially when undertaken by untrained providers with inappropriate equipment.

Dr Helen Weiss, from the London School of Hygiene & Tropical Medicine, UK, studied the medical literature relating to circumcision. Dr Weiss mentioned, “We identified 52 studies from 21 countries which included sufficient information to estimate frequency of adverse events following neonatal, infant and child circumcision. This forms a systematic review with the published literature on complications linked using the procedure at young ages.”

The researchers found that amongst infants aged less than one year old, the frequency of relatively minor adverse events like excessive bleeding, swelling and infection was low (median 1.5% for any adverse event) and severe complications had been very rare. Circumcisions by medical providers on children aged 1 year or older tended to be associated with a lot more complications (median 6%), although there were still few significant adverse events. Nevertheless, much more complications, which includes severe complications, were seen when the procedure was undertaken by inexperienced providers, or with inadequate equipment and supplies.

Dr Weiss mentioned, “Male circumcision is commonly practiced and will continue to occur for religious, cultural and medical reasons. There’s a clear have to improve safety of male circumcision at all ages through improved training or re-training for each traditional and medically trained providers, and to ensure that providers have adequate supplies of necessary equipment and instruments for safe circumcision”.

Notes:
Complications of circumcision in male neonates, infants and children: a systematic review
Helen A Weiss, Natasha Larke, Daniel Halperin and Inon Schenker
BMC Urology (in press)
Article available at journal website: http://www.biomedcentral.com/bmcurol/

Source:
Graeme Baldwin
BioMed Central

4.67 (3 votes)

Healthcare Prof:

4 (1 votes)

A team led by PhD researcher Dr Colleen Lau from the School of Population Health http://www.sph.uq.edu.au/, has discovered the disease, known medically as leptospirosis, was traditionally a concern for males working in the agricultural and livestock industries, as it’s contracted from contact with the urine of host animals.

Ms Lau stated recreational exposure and international travel have emerged as increasingly important sources of infection more than the past decade.

“Many of the areas having a high incidence of leptospirosis are popular destinations for domestic and international travellers,” Dr Lau stated.

“With the rising popularity of ecotourism and outdoor adventure activities, travellers are probably to become increasingly exposed by means of activities that involve contact with freshwater, soil and animals.”

Leptospirosis causes influenza-like symptoms for example fever, chills, headache and jaundice but can result in a lot more critical illness which includes kidney failure, liver failure, lung haemorrhage, brain infections, and can occasionally be fatal.

Called canecutter’s illness in Queensland due to the spread with the disease by canefield rats, the study, published in the journal Travel Medicine and Infectious Disease (click here for abstract), has opened up a brand new way of looking in the spread with the illness.

As an under-diagnosed trigger of fever in adventure seekers and returned travellers, Dr Lau and her co-authors, Professor Phil Weinstein and Lee Smythe, urged clinicians to change their perceptions with the population at threat of contracting leptospirosis, even if they do not fit the mould of a male agricultural worker.

“Early recognition, diagnosis, and therapy will reduce the incidence of severe illness and deaths,” she stated.

Known high-risk areas for leptospirosis include tropical and subtropical regions like Queensland, New Zealand, the Pacific Islands, parts of South East Asia and the Caribbean.

Dr Lau is working in one such island, American Samoa, to complete her PhD on an analysis of risk factors for contracting leptospirosis.

Source:
Jeann Wong
Research Australia

4.43 (7 votes)

Healthcare Prof:

3 (2 votes)

Male breast cancer is really a relatively rare cancer in guys that originates from the breast. Most circumstances of male breast cancer create in males who are 65 years of age, or over, although cases have been recorded in men aged who are among 20-90 years of age.

Breast cancer is 100 times far more typical in girls than in guys. The American Cancer Society estimates that each year, about 1,990 new cases of breast cancer in men will be diagnosed and that breast cancer will cause roughly 480 deaths in males. A man’s lifetime threat of developing breast cancer is about one in one thousand.

The estimated five year survival rate for early-stage male breast cancer is 75-100%. For mid-stage male breast cancer it’s 50-80%, and for advanced-stage male breast cancer there is certainly 30-60% chance of survival right after five years from detection.

What are the symptoms of Male Breast Cancer?A symptom is something the patient senses and describes, although a sign is something other people, like the doctor notice. For example, drowsiness might be a symptom even though dilated pupils could be a sign.

Adjusted for age and stage the prognosis for breast cancer in males is similar to that in females. Men will experience smaller tumor size and absence or paucity of local lymph node involvement. Hormonal treatment may possibly be connected with hot flashes and impotence.

The most common symptom of male breast cancer is the appearance of a lump inside the breast. In most instances, the lump will be painless.

Less typical symptoms of male breast cancer usually affect the nipple. Such symptoms contain nipple retraction, ulceration and discharge, exactly where fluid begins to leak from the nipple.

If the cancer spreads additional symptoms may possibly include breast pain, bone pain, and swelling with the lymph nodes (glands) near the breast, usually in or around, the armpit.

What are the causes of Male Breast Cancer? It truly is not known for certain what causes the cells within the breast to become cancerous. Nevertheless, a number of threat factors for male breast cancer have been identified.

About 85% of breast cancers in men have estrogen receptors on their cell membranes. Estrogen receptors on the cell membranes allow estrogen molecules to bind towards the cancer cells. Estrogen binding towards the cancer cells stimulates cell growth and multiplication.

Klinefelter’s syndrome is actually a main threat factor for male breast cancer because guys using the condition are 20 times more probably to create male breast cancer than the male population at large. Klinefelter’s syndrome is where baby boys are born with much higher levels of estrogen than normal.

A number of mutated genes have been linked to an improve danger of male breast cancer. For example, a mutation known as the BRAC2 mutation has been identified in an estimated 5% of males with male breast cancer.

There is also evidence that male breast cancer can run in families, as 1 in five men who create breast cancer, have a first-degree male relative, such as a father, or brother, who also has a history of breast cancer.

Diagnosing Male Breast CancerTypically self-examination leads towards the detection of a lump within the breast which requires further investigation.

Biopsy, ultrasound and mammography might be sometimes utilized for further definition.

What are the therapy options for Male Breast Cancer? Surgery is usually the very first therapy option for male breast cancer, and usually involves an operation called a modified radical mastectomy. This involves the surgeon removing the entire breast as well as the lymph nodes inside the armpit.

Estrogen hormone therapy might be used in cases of male breast cancer exactly where there are estrogen receptors on the walls of the cancerous cells. This implies that the cells can use estrogen to help them grow and reproduce. Therefore, the aim of hormone therapy would be to block the effects of estrogen. In addition, Tamoxifen can be a widely employed medication in hormone therapy. It works by blocking the estrogen receptors so that estrogen is unable to enter into cancerous cells. In another remedy option, aromatase inhibitors block the effects with the aromatase protein which, in turn, lowers the amount of estrogen in the body.

Chemotherapy is utilised to treat instances of male breast cancer where the cancerous cells do not have estrogen receptors, meaning that hormone therapy would be mostly ineffective. Chemotherapy is usually given soon after surgery so that you can avoid the cancer returning, or it is utilized to treat the symptoms of incurable cancer.

Preventing Male Breast Cancer Early detection can help stop the spread of cancer. If there is a history of male breast cancer within the household, a person should check regularly for lumps and report any modifications to a doctor as soon as feasible.

In general, top a wholesome lifestyle is really a excellent way to help prevent male breast cancer, together with numerous other significant well being conditions.

Written by Sy Kraft (B.A.)
Copyright: Medical News Today
Not to be reproduced with no permission of Medical News These days

4.84 (25 votes)

Healthcare Prof:

4.69 (13 votes)

Article Opinions:1 posts

The Related Press examines efforts to prevent the spread of HIV by circumcising “about 50 million guys across Africa – where 70 percent of the world’s HIV-infected population lives.” The procedure has been shown to lower a man’s threat of HIV infection by way of heterosexual sex, prompting “[c]ountries with high HIV rates, such as Botswana, Kenya, Rwanda, Namibia and Zambia,” to include male circumcision in their HIV prevention plans, the news service writes.

The AP looks at a brand new male circumcision device that according to researchers is less painful and requires much less time for health workers compared to traditional circumcision techniques. The Chinese-developed “ShangRing consists of two plastic rings, one slightly smaller than the other, that trap the foreskin in in between them. With the use of some anesthesia, the foreskin can then be snipped off with out significant bleeding or stitches. The device is kept on for ten days to allow the wound to heal,” the news service writes.

“According to Chinese information, the complication rate in thousands of men who have had the ShangRing is less than five percent,” even though with “traditional circumcisions in Africa, it can be as high as 15 percent. A surgical circumcision takes about 20 minutes; 1 using the ShangRing might be done in about five. … Inside the 40 males tested in Kenya, 90 percent mentioned they had been satisfied using the procedure,” the AP reports.

According towards the news service, researchers are scheduled to launch a larger study in Kenya later this year. The Bill & Melinda Gates Foundation plans to spend $4 million to support studies evaluating ShangRing and is examining other adult male circumcision devices, the AP reports.

According to “Kim Dickson, an AIDS expert in the World Wellness Organization, … mass circumcision could avoid about four million adult HIV infections between 2009 and 2025,” the AP reports. “Circumcision will most likely avert far far more deaths per dollar spent than other things we’re spending HIV money on,” Philip Stevens, with the International Policy Network, said. “The main problem I can foresee with this is actually persuading men to sign up for it.”

The post anotes that “[e]xperts are also concerned males who get circumcised will mistakenly think they are immune to HIV” (Cheng, 2/15).

This information was reprinted from globalhealth.kff.org with type permission from the Henry J. Kaiser Family Foundation. It is possible to view the whole Kaiser Every day Global Health Policy Report, search the archives and sign up for e-mail delivery at globalhealth.kff.org.

? Henry J. Kaiser Family Foundation. All rights reserved.

Healthcare Prof:

4 (1 votes)

Merck’s human papillomavirus vaccine, Gardasil, effectively prevented precancerous cervical lesions and genital warts in women ages 24 through 45, and it prevented anal cancer and precancerous anal lesions in young men who’ve sex with guys, based on two studies released by the organization on Wednesday, the AP/Philadelphia Inquirer reports. Merck released the studies in conjunction using a European conference of physicians and researchers who specialize in cancer and genital infections.

Gardasil at the moment is approved for the prevention of cervical cancer and genital warts in girls and females ages nine through 26. Merck is utilizing the information from the women’s study to assistance its application for FDA approval to industry Gardasil for cervical cancer and genital wart prevention in females up to age 45. The company expects a ruling by June on the application to make use of the vaccine in older women (Johnson, AP/Philadelphia Inquirer, 2/17).

Gardasil helps block four with the most typical HPV strains — two types that cause 70% of cervical cancer circumstances and two other varieties that trigger 90% of genital warts cases (Women’s Well being Policy Report, 10/22/09). The vaccine also is approved to stop genital warts in boys and males ages nine by way of 26. Gardasil is amongst Merck’s 10 best-selling products, generating $1.12 billion in sales in 2009.

In late 2009, Merck, which funded each studies, provided FDA with more-detailed information from the women’s study. The agency previously rejected the company’s request to market the drug to older females and requested longer-term follow-up data. The newly released women’s study tracked participants for an further one and 1 half years. The study involved 3,819 females ages 24 by way of 45 from several nations who did not have cervical cancer, genital warts or HPV, the AP/Inquirer reports. Precancerous cervical lesions and genital warts did not take place in about 89% of the ladies who received 3 injections of Gardasil more than six months, compared with girls in a group that received a placebo shot. Twenty-three women receiving the placebo and 1 woman who was vaccinated created lesions or warts. All participants had been periodically examined for an average of about 4 years, the AP/Inquirer reports.

The second study located that 3 injections of Gardasil prevented precancerous anal lesions and anal cancer in about 77% of young guys. Whilst no males in either the Gardasil group or perhaps a placebo group created anal cancer, 24 who received the placebo and five who were vaccinated created precancerous lesions. The males were tracked for an average of three years right after the very first shot. According to Merck spokesperson Pam Eisele, the firm plans to submit data on anal cancer in men to FDA and apply for advertising approval (AP/Philadelphia Inquirer, 2/17).

Reprinted with kind permission from http://www.nationalpartnership.org. It is possible to view the whole Daily Women’s Health Policy Report, search the archives, or sign up for e-mail delivery here. The Day-to-day Women’s Health Policy Report is a free service with the National Partnership for Ladies & Families, published by The Advisory Board Company.

? 2010 The Advisory Board Business. All rights reserved.

View drug data on Gardasil.

5 (1 votes)

Healthcare Prof:

Measuring levels with the active form of the protein EGFR within the tumor and its vicinity can give a much more trustworthy prognosis for people with prostate cancer. This is what Ume? University researcher Peter Hammarsten and his associates write in a study in the leading scientific journal Clinical Cancer Study.

One of the main problems with prostate cancer is the fact that, with today’s prognosis markers, some 70-80 percent of patients wind up in a group where quite small may be mentioned about their prognosis. However, nowadays no techniques to are great enough establish which patients truly need to have therapy and which ones can get along fine without the hard remedy. This in turn implies that certain patients are over-treated with therapies that may result in serious side effects and that other patients who actually require intensive remedy don’t get it or get it too late.

In a study lately published inside the scientific journal Clinical Cancer Research, Hammarsten studied tissue biopsies from prostate tumors in 259 patients and located a new prognosis marker for prostate cancer. It’s the active type of the protein EFGR (Epidermal Growth Factor Receptor) that was shown to give data regarding the aggressiveness of the tumor, each when it’s measured within the tumor or within the healthy tissue surrounding the tumor.

EGFR belongs to the same household as the prognosis marker HER2, that is utilized right now for breast cancer to decide the aggressiveness of a tumor which is to be treated with inhibitors of HER2, that’s, the drug Herceptin. In a comparable way, it might be feasible in the future to use the active type of EGFR to choose patients having a poor prognosis and are appropriate for remedy with inhibitors of EGFR. As a way to use EGFR as a prognosis marker clinically within the future, further studies will have to target its expressions in other and bigger material in prostate tumors.

Prostate cancer may be the most frequent cancer form among guys in Sweden. Each year some 10,000 men are diagnosed with prostate cancer. Some two,500 of them will die of their disease. In other words, some patients have an aggressive fatal illness, whereas others have a slowly growing tumor that can not trigger any key troubles.

Source: Expertanswer

View drug info on Herceptin.